R-454B Refrigerant (HFO, A2L)

R-454B Refrigerant – Low-GWP HFO (A2L)

R-454B is a next-generation HFO blend designed as a lower-GWP alternative to R-410A in new air conditioning and heat pump equipment. It offers comparable capacity and efficiency while helping meet evolving environmental regulations. R-454B is classified as A2L (mildly flammable); always follow manufacturer guidance and local codes.

Common Applications

  • New residential and light-commercial A/C and heat pumps (OEM-specified equipment)
  • Chillers and packaged systems engineered for A2L refrigerants

Cylinder Sizes & Packaging

  • 20 lb cylinder (typical service size)

Key Advantages

  • Lower GWP compared to R-410A
  • High performance in systems designed for A2L refrigerants
  • OEM support in many next-gen A/C and heat-pump platforms

Important Notes

  • Not a drop-in for R-410A equipment. Use only in systems specifically designed and rated for R-454B.
  • Handling & shipping: May require hazmat procedures; follow label, SDS, and carrier rules.
  • Certification: Certain purchases may require EPA Section 608 credentials; verify federal, state, and local requirements.

Comparing options? See R-410A and R-32, or browse our HFO Refrigerants (Low GWP).

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